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Symbol
Name
ID

Thra
thyroid hormone receptor alpha
MGI:98742

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Increased T3/T4 ratio	Congenital hypothyroidism	Impaired sensitivity to thyroid hormone
Disease(s) Associated with THRA
congenital nongoitrous hypothyroidism 6

Mouse Phenotypes		abnormal pancreatic islet morphology	small pancreatic islets	abnormal thyroid follicle morphology	thyroid gland hypoplasia	increased glucagon secretion	abnormal insulin secretion	increased insulin secretion	abnormal thyroid gland physiology	decreased activity of thyroid gland	increased activity of thyroid gland
Availability	Mouse Genotype	abnormal pancreatic islet morphology	small pancreatic islets	abnormal thyroid follicle morphology	thyroid gland hypoplasia	increased glucagon secretion	abnormal insulin secretion	increased insulin secretion	abnormal thyroid gland physiology	decreased activity of thyroid gland	increased activity of thyroid gland
	Thra^tm1.1Fcas/Thra^tm1.1Fcas
	Thra^tm1Jas/Thra^tm1Jas
	Thra^tm1Ven/Thra^tm1Ven
	Thra^tm2Jas/Thra^tm2Jas
	Thra^tm2Ven/Thra^tm2Ven
	Thra^tm2Ven/Thra⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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